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Journal cover image

Activity-Dependent Transcription Collaborates with Local Dendritic Translation to Encode Stimulus-Specificity in the Genome Binding of NPAS4.

Publication ,  Journal Article
West, AE
Published in: Neuron
November 20, 2019

A new study in Cell (Brigidi et al., 2019) shows that local dendritic versus somatic translation of the neuronal activity-inducible transcription factor NPAS4 drives the formation of distinct heterodimers that enable stimulus-specificity to be encoded into the pattern of NPAS4 binding across the genome.

Duke Scholars

Published In

Neuron

DOI

EISSN

1097-4199

Publication Date

November 20, 2019

Volume

104

Issue

4

Start / End Page

634 / 636

Location

United States

Related Subject Headings

  • Neurons
  • Neurology & Neurosurgery
  • Genomics
  • Gene Expression Regulation
  • Dendrites
  • Basic Helix-Loop-Helix Transcription Factors
  • 5202 Biological psychology
  • 3209 Neurosciences
  • 1702 Cognitive Sciences
  • 1701 Psychology
 
Journal cover image

Published In

Neuron

DOI

EISSN

1097-4199

Publication Date

November 20, 2019

Volume

104

Issue

4

Start / End Page

634 / 636

Location

United States

Related Subject Headings

  • Neurons
  • Neurology & Neurosurgery
  • Genomics
  • Gene Expression Regulation
  • Dendrites
  • Basic Helix-Loop-Helix Transcription Factors
  • 5202 Biological psychology
  • 3209 Neurosciences
  • 1702 Cognitive Sciences
  • 1701 Psychology