Transplantation without pretransplant therapy: Is this a possibility? Insights into providing transplantation at diagnosis for patients with acute leukemia.

Journal Article (Journal Article;Review)

Allogeneic hematopoietic stem cell transplantation (HSCT) has the potential for providing a cure for several hematologic malignancies. Although in most circumstances, allogeneic HSCT is preceded by disease-directed or cytoreductive therapy, it is unclear if these toxic conditioning regimens can be circumvented. This review summarizes evidence that will provide insights into factors that influence outcomes in allogeneic HSCT and whether this curative therapy could be used right at diagnosis.

Full Text

Duke Authors

Cited Authors

  • Chao, NJ

Published Date

  • December 2019

Published In

Volume / Issue

  • 32 / 4

Start / End Page

  • 101108 -

PubMed ID

  • 31779981

Electronic International Standard Serial Number (EISSN)

  • 1532-1924

Digital Object Identifier (DOI)

  • 10.1016/j.beha.2019.101108


  • eng

Conference Location

  • Netherlands