A Novel Mechanism for Th17 Inflammation in Human Type 2 Diabetes Mellitus.

Journal Article (Journal Article)

In their recent study, Nicholas et al. challenge the current dogma that T cell inflammation must be fueled by glycolysis and demonstrate a novel metabolic mechanism for Th17 inflammation in human type 2 diabetes mellitus (T2DM): a combination of increased environmental long-chain fatty acid metabolites coupled with decreased fatty acid oxidation.

Full Text

Duke Authors

Cited Authors

  • Kiernan, K; MacIver, NJ

Published Date

  • January 2020

Published In

Volume / Issue

  • 31 / 1

Start / End Page

  • 1 - 2

PubMed ID

  • 31767267

Electronic International Standard Serial Number (EISSN)

  • 1879-3061

Digital Object Identifier (DOI)

  • 10.1016/j.tem.2019.11.002


  • eng

Conference Location

  • United States