Persistence of H7N9 virus antibody response 2 years after infection.

Journal Article (Journal Article)

We measured antibodies against H7N9 virus 2 years after infection in 14 patients who were infected during October 2016-September 2017. Approximately 2 years after infection, antibody titers ≥10 were detectable in 13 (92.9%) patients. Three (21.4%) of 14 patients had hemagglutination inhibition titers ≥40, and their geometric mean titer (GMT) was 20 (95% CI 15.7-28.1), whereas 10 (71.4%) and all 14 (100%) of the 14 patients had titers ≥40, and GMTs at 34.4 (95% CI 25.7-51.2) and 73.45 (54.7-106.7) for neuraminidase inhibition and microneutralization antibodies, respectively. Our findings suggest that H7N9 infection may induce long-term antibody response at least 2 years after infection.

Full Text

Duke Authors

Cited Authors

  • Yao, L; Wang, G-L; Chen, L-L; Liu, C; Duan, L-J; Gray, GC; Ma, M-J

Published Date

  • March 2020

Published In

Volume / Issue

  • 14 / 2

Start / End Page

  • 210 - 214

PubMed ID

  • 31856341

Pubmed Central ID

  • PMC7040969

Electronic International Standard Serial Number (EISSN)

  • 1750-2659

Digital Object Identifier (DOI)

  • 10.1111/irv.12702

Language

  • eng

Conference Location

  • England