Act globally, think locally: systems biology addresses the PDZ domain.

Journal Article (Review;Journal Article)

Interaction networks, cartography and mapping, wiring and circuitry, whichever metaphor is invoked, the cardinal questions regarding cellular proteins are the same: What are they? How much is there? What do they do, and to whom do they do it? One of the more recent proteomics tools to pursue these lines of inquiry is the protein microarray, and a current report has unleashed this formidable technique upon a target of considerable biological interest, the PDZ domain family of signaling molecules.

Full Text

Duke Authors

Cited Authors

  • Spaller, MR

Published Date

  • May 2006

Published In

Volume / Issue

  • 1 / 4

Start / End Page

  • 207 - 210

PubMed ID

  • 17163673

Electronic International Standard Serial Number (EISSN)

  • 1554-8937

International Standard Serial Number (ISSN)

  • 1554-8929

Digital Object Identifier (DOI)

  • 10.1021/cb600191y


  • eng