Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line.
Journal Article (Journal Article)
A mixed-oligonucleotide probe was used to identify four ras-like coding sequences in a human teratocarcinoma cDNA library. Two of these sequences resembled the rho genes, one was closely related to H-, K-, and N-ras, and one shared only the four sequence domains that define the ras gene superfamily. Homologs of the four genes were found in genomic DNA from a variety of mammals and from chicken. The genes were transcriptionally active in a range of human cell types.
Full Text
Duke Authors
Cited Authors
- Drivas, GT; Shih, A; Coutavas, E; Rush, MG; D'Eustachio, P
Published Date
- April 1990
Published In
Volume / Issue
- 10 / 4
Start / End Page
- 1793 - 1798
PubMed ID
- 2108320
Pubmed Central ID
- PMC362288
International Standard Serial Number (ISSN)
- 0270-7306
Digital Object Identifier (DOI)
- 10.1128/mcb.10.4.1793-1798.1990
Language
- eng
Conference Location
- United States