Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line.

Journal Article (Journal Article)

A mixed-oligonucleotide probe was used to identify four ras-like coding sequences in a human teratocarcinoma cDNA library. Two of these sequences resembled the rho genes, one was closely related to H-, K-, and N-ras, and one shared only the four sequence domains that define the ras gene superfamily. Homologs of the four genes were found in genomic DNA from a variety of mammals and from chicken. The genes were transcriptionally active in a range of human cell types.

Full Text

Duke Authors

Cited Authors

  • Drivas, GT; Shih, A; Coutavas, E; Rush, MG; D'Eustachio, P

Published Date

  • April 1990

Published In

Volume / Issue

  • 10 / 4

Start / End Page

  • 1793 - 1798

PubMed ID

  • 2108320

Pubmed Central ID

  • PMC362288

International Standard Serial Number (ISSN)

  • 0270-7306

Digital Object Identifier (DOI)

  • 10.1128/mcb.10.4.1793-1798.1990

Language

  • eng

Conference Location

  • United States