Sustained Sexual Behavior Change After Acute HIV Diagnosis in Malawi.

Journal Article (Journal Article)

BACKGROUND: Identification of acute HIV infection (AHI) allows for important opportunities for HIV prevention through behavior change and biomedical intervention. Here, we evaluate changes in sexual risk behaviors among persons with AHI enrolled in a combined behavioral and biomedical intervention designed to reduce onward transmission of HIV. METHODS: Participants were randomized to standard HIV counseling, a multisession behavioral intervention, or a multisession behavioral intervention plus antiretrovirals. Sexual behaviors were assessed periodically over 1 year. RESULTS: Four weeks after diagnosis, the predicted probability of reporting multiple sexual partners decreased from 24% to 9%, and the probability of reporting unprotected sex decreased from 71% to 27%. These declines in sexual risk behaviors were sustained over follow-up irrespective of study arm. CONCLUSIONS: Diagnosis of AHI alone may be sufficient to achieve immediate and sustained behavior change during this highly infectious period.

Full Text

Duke Authors

Cited Authors

  • Rucinski, KB; Rutstein, SE; Powers, KA; Pasquale, DK; Dennis, AM; Phiri, S; Hosseinipour, MC; Kamanga, G; Nsona, D; Massa, C; Hoffman, IF; Miller, WC; Pettifor, AE

Published Date

  • November 2018

Published In

Volume / Issue

  • 45 / 11

Start / End Page

  • 741 - 746

PubMed ID

  • 29870501

Pubmed Central ID

  • PMC6179914

Electronic International Standard Serial Number (EISSN)

  • 1537-4521

Digital Object Identifier (DOI)

  • 10.1097/OLQ.0000000000000873


  • eng

Conference Location

  • United States