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Combination Therapy for Invasive Fungal Infections

Publication ,  Journal Article
Livengood, SJ; Drew, RH; Perfect, JR
Published in: Current Fungal Infection Reports
March 1, 2020

Purpose of the Review: The purpose of this review is to summarize and evaluate relevant literature on combination antifungal therapy for invasive fungal infections (IFIs). Recent Findings: Cryptococcal meningitis has the largest body and highest quality in support of combination therapy with amphotericin B and flucytosine. More recent data in treatment of invasive aspergillosis suggest combination therapy with voriconazole and echinocandins may be effective in select patients. Quality studies are needed to define combination therapy in rare mold infections. Summary: Multiple strategies have been employed to optimize treatment of the growing incidence of IFIs. With exceptions as noted above, justification for the use of combination antifungal therapy is most often based on uncontrolled and/or underpowered studies, in vitro data, and case reports.

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Published In

Current Fungal Infection Reports

DOI

EISSN

1936-377X

ISSN

1936-3761

Publication Date

March 1, 2020

Volume

14

Issue

1

Start / End Page

40 / 49

Related Subject Headings

  • 3207 Medical microbiology
  • 3202 Clinical sciences
 

Citation

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Livengood, S. J., Drew, R. H., & Perfect, J. R. (2020). Combination Therapy for Invasive Fungal Infections. Current Fungal Infection Reports, 14(1), 40–49. https://doi.org/10.1007/s12281-020-00369-4
Livengood, S. J., R. H. Drew, and J. R. Perfect. “Combination Therapy for Invasive Fungal Infections.” Current Fungal Infection Reports 14, no. 1 (March 1, 2020): 40–49. https://doi.org/10.1007/s12281-020-00369-4.
Livengood SJ, Drew RH, Perfect JR. Combination Therapy for Invasive Fungal Infections. Current Fungal Infection Reports. 2020 Mar 1;14(1):40–9.
Livengood, S. J., et al. “Combination Therapy for Invasive Fungal Infections.” Current Fungal Infection Reports, vol. 14, no. 1, Mar. 2020, pp. 40–49. Scopus, doi:10.1007/s12281-020-00369-4.
Livengood SJ, Drew RH, Perfect JR. Combination Therapy for Invasive Fungal Infections. Current Fungal Infection Reports. 2020 Mar 1;14(1):40–49.
Journal cover image

Published In

Current Fungal Infection Reports

DOI

EISSN

1936-377X

ISSN

1936-3761

Publication Date

March 1, 2020

Volume

14

Issue

1

Start / End Page

40 / 49

Related Subject Headings

  • 3207 Medical microbiology
  • 3202 Clinical sciences