De Novo Centromere Formation: One's Company, Two's a Crowd.

Journal Article (Journal Article)

Chromosomes containing two centromeres (dicentrics) trigger chromosome instability that is avoided by the enigmatic process of centromere inactivation. In this issue of Developmental Cell, Palladino et al. (2020) combine in vivo chromosome engineering and Drosophila genetics to assess consequences of de novo centromere formation and clarify models of centromere inactivation.

Full Text

Duke Authors

Cited Authors

  • Sullivan, BA

Published Date

  • February 10, 2020

Published In

Volume / Issue

  • 52 / 3

Start / End Page

  • 257 - 258

PubMed ID

  • 32049036

Electronic International Standard Serial Number (EISSN)

  • 1878-1551

Digital Object Identifier (DOI)

  • 10.1016/j.devcel.2020.01.021


  • eng

Conference Location

  • United States