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Report of the NIH Task Force on research standards for chronic low back pain.

Publication ,  Journal Article
Deyo, RA; Dworkin, SF; Amtmann, D; Andersson, G; Borenstein, D; Carragee, E; Carrino, J; Chou, R; Cook, K; DeLitto, A; Goertz, C; Khalsa, P ...
Published in: J Pain
June 2014

UNLABELLED: Despite rapidly increasing intervention, functional disability due to chronic low back pain (cLBP) has increased in recent decades. We often cannot identify mechanisms to explain the major negative impact cLBP has on patients' lives. Such cLBP is often termed non-specific and may be due to multiple biologic and behavioral etiologies. Researchers use varied inclusion criteria, definitions, baseline assessments, and outcome measures, which impede comparisons and consensus. Therefore, NIH Pain Consortium charged a Research Task Force (RTF) to draft standards for research on cLBP. The resulting multidisciplinary panel recommended using 2 questions to define cLBP; classifying cLBP by its impact (defined by pain intensity, pain interference, and physical function); use of a minimum dataset to describe research participants (drawing heavily on the PROMIS methodology); reporting "responder analyses" in addition to mean outcome scores; and suggestions for future research and dissemination. The Pain Consortium has approved the recommendations, which investigators should incorporate into NIH grant proposals. The RTF believes that these recommendations will advance the field, help to resolve controversies, and facilitate future research addressing the genomic, neurologic, and other mechanistic substrates of chronic low back pain. We expect that the RTF recommendations will become a dynamic document and undergo continual improvement. PERSPECTIVE: A task force was convened by the NIH Pain Consortium with the goal of developing research standards for chronic low back pain. The results included recommendations for definitions, a minimum dataset, reporting outcomes, and future research. Greater consistency in reporting should facilitate comparisons among studies and the development of phenotypes.

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Published In

J Pain

DOI

EISSN

1528-8447

Publication Date

June 2014

Volume

15

Issue

6

Start / End Page

569 / 585

Location

United States

Related Subject Headings

  • United States
  • Research Design
  • Research
  • Pain Measurement
  • National Institutes of Health (U.S.)
  • Low Back Pain
  • Humans
  • Chronic Pain
  • Anesthesiology
  • Advisory Committees
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Deyo, R. A., Dworkin, S. F., Amtmann, D., Andersson, G., Borenstein, D., Carragee, E., … Weiner, D. K. (2014). Report of the NIH Task Force on research standards for chronic low back pain. J Pain, 15(6), 569–585. https://doi.org/10.1016/j.jpain.2014.03.005
Deyo, Richard A., Samuel F. Dworkin, Dagmar Amtmann, Gunnar Andersson, David Borenstein, Eugene Carragee, John Carrino, et al. “Report of the NIH Task Force on research standards for chronic low back pain.J Pain 15, no. 6 (June 2014): 569–85. https://doi.org/10.1016/j.jpain.2014.03.005.
Deyo RA, Dworkin SF, Amtmann D, Andersson G, Borenstein D, Carragee E, et al. Report of the NIH Task Force on research standards for chronic low back pain. J Pain. 2014 Jun;15(6):569–85.
Deyo, Richard A., et al. “Report of the NIH Task Force on research standards for chronic low back pain.J Pain, vol. 15, no. 6, June 2014, pp. 569–85. Pubmed, doi:10.1016/j.jpain.2014.03.005.
Deyo RA, Dworkin SF, Amtmann D, Andersson G, Borenstein D, Carragee E, Carrino J, Chou R, Cook K, DeLitto A, Goertz C, Khalsa P, Loeser J, Mackey S, Panagis J, Rainville J, Tosteson T, Turk D, Von Korff M, Weiner DK. Report of the NIH Task Force on research standards for chronic low back pain. J Pain. 2014 Jun;15(6):569–585.
Journal cover image

Published In

J Pain

DOI

EISSN

1528-8447

Publication Date

June 2014

Volume

15

Issue

6

Start / End Page

569 / 585

Location

United States

Related Subject Headings

  • United States
  • Research Design
  • Research
  • Pain Measurement
  • National Institutes of Health (U.S.)
  • Low Back Pain
  • Humans
  • Chronic Pain
  • Anesthesiology
  • Advisory Committees