Oral cavity cancer: Diagnosis and treatment

Book Section

A comprehensive history, thorough head and neck physical examination, and adequate staging are critical to guide optimal locoregional treatment and evaluate for second primaries in patients with oral cavity cancer. A multidisciplinary approach-including head and neck surgery, radiation and medical oncology, pathology, radiology, nursing, dentistry, dietary, speech, and social work-is paramount for optimal management. Early-stage disease is typically treated with surgery alone, but in certain circumstances radiotherapy alone is preferred. Locally advanced disease is generally managed with upfront surgery and postoperative radiotherapy, with concomitant chemotherapy reserved for high-risk features such as positive surgical margins and extranodal extension.

Full Text

Duke Authors

Cited Authors

  • Jacobs, CD; Moravan, MJ; Choe, J; Kahmke, R; Mowery, Y; Salama, JK

Published Date

  • January 1, 2018

Book Title

  • Encyclopedia of Cancer

Start / End Page

  • 131 - 168

International Standard Book Number 13 (ISBN-13)

  • 9780128124857

Digital Object Identifier (DOI)

  • 10.1016/B978-0-12-801238-3.65316-3

Citation Source

  • Scopus