Extended Oral Antibiotics and Infection Prophylaxis after a Primary or Revision Total Knee Arthroplasty.

Journal Article (Journal Article;Review)

One of the most common reasons for failure of primary total knee arthroplasty and need for revision surgery is periprosthetic infection. Antibiotics are one of the mainstays of treatment to address prosthetic joint infections, but the route of administration and timing of delivery to optimize patient outcomes are debated. This article reviews the use and attributes of commonly used oral antibiotics, especially extended or long-term utilization, as prophylaxis and treatment for prosthetic joint infections in a primary or revision total knee arthroplasty, which include debridement, antibiotics, and implant retention, one-stage and two-stage exchange arthroplasty.

Full Text

Duke Authors

Cited Authors

  • Hong, CS; Black, CS; Ryan, SP; Seyler, TM

Published Date

  • February 2020

Published In

Volume / Issue

  • 33 / 2

Start / End Page

  • 111 - 118

PubMed ID

  • 31797341

Electronic International Standard Serial Number (EISSN)

  • 1938-2480

Digital Object Identifier (DOI)

  • 10.1055/s-0039-3400755


  • eng

Conference Location

  • Germany