Unified approaches to assessing treatment effect of traditional Chinese medicine based on health profiles.

Journal Article (Journal Article)

Two dissimilarity indices are introduced to measure the disharmony of a human body system by mimicking the population bioequivalence and the individual bioequivalence concepts. Hypotheses for the treatment effect of a traditional Chinese medicine are formulated based on the two indices and then tested under the proposed designs by reverting an approximate confidence upper bound. The proposed methods can also be used when a drug product has multiple components or a trial has multiple endpoints.

Full Text

Duke Authors

Cited Authors

  • Cheng, B; Zhang, B; Chow, S-C

Published Date

  • May 3, 2020

Published In

Volume / Issue

  • 30 / 3

Start / End Page

  • 564 - 573

PubMed ID

  • 32065018

Electronic International Standard Serial Number (EISSN)

  • 1520-5711

Digital Object Identifier (DOI)

  • 10.1080/10543406.2020.1726368

Language

  • eng

Conference Location

  • England