Skip to main content
Journal cover image

Replay of cortical spiking sequences during human memory retrieval.

Publication ,  Journal Article
Vaz, AP; Wittig, JH; Inati, SK; Zaghloul, KA
Published in: Science
March 6, 2020

Episodic memory retrieval is thought to rely on the replay of past experiences, yet it remains unknown how human single-unit activity is temporally organized during episodic memory encoding and retrieval. We found that ripple oscillations in the human cortex reflect underlying bursts of single-unit spiking activity that are organized into memory-specific sequences. Spiking sequences occurred repeatedly during memory formation and were replayed during successful memory retrieval, and this replay was associated with ripples in the medial temporal lobe. Together, these data demonstrate that human episodic memory is encoded by specific sequences of neural activity and that memory recall involves reinstating this temporal order of activity.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Science

DOI

EISSN

1095-9203

Publication Date

March 6, 2020

Volume

367

Issue

6482

Start / End Page

1131 / 1134

Location

United States

Related Subject Headings

  • Temporal Lobe
  • Mental Recall
  • Memory, Episodic
  • Male
  • Humans
  • General Science & Technology
  • Female
  • Electroencephalography
  • Adult
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Vaz, A. P., Wittig, J. H., Inati, S. K., & Zaghloul, K. A. (2020). Replay of cortical spiking sequences during human memory retrieval. Science, 367(6482), 1131–1134. https://doi.org/10.1126/science.aba0672
Vaz, Alex P., John H. Wittig, Sara K. Inati, and Kareem A. Zaghloul. “Replay of cortical spiking sequences during human memory retrieval.Science 367, no. 6482 (March 6, 2020): 1131–34. https://doi.org/10.1126/science.aba0672.
Vaz AP, Wittig JH, Inati SK, Zaghloul KA. Replay of cortical spiking sequences during human memory retrieval. Science. 2020 Mar 6;367(6482):1131–4.
Vaz, Alex P., et al. “Replay of cortical spiking sequences during human memory retrieval.Science, vol. 367, no. 6482, Mar. 2020, pp. 1131–34. Pubmed, doi:10.1126/science.aba0672.
Vaz AP, Wittig JH, Inati SK, Zaghloul KA. Replay of cortical spiking sequences during human memory retrieval. Science. 2020 Mar 6;367(6482):1131–1134.
Journal cover image

Published In

Science

DOI

EISSN

1095-9203

Publication Date

March 6, 2020

Volume

367

Issue

6482

Start / End Page

1131 / 1134

Location

United States

Related Subject Headings

  • Temporal Lobe
  • Mental Recall
  • Memory, Episodic
  • Male
  • Humans
  • General Science & Technology
  • Female
  • Electroencephalography
  • Adult