Foundations and application of precision medicine


Book Section

© 2019 Elsevier Inc. All rights reserved. The goal of precision medicine is to optimize disease prevention, diagnosis, and treatment decision-making through the assimilation and analysis of multiple types of data including both genotypic (DNA variation) and phenotypic measures (traditional clinical biomarkers, gene expression, and metabolite profile). Successful integration of new data and analytical methods will pivot on a robust and secure clinical infrastructure, electronic medical records and digital health technologies. Precision medicine may be integrated into public health surveillance, preventive care, and diagnosis. This chapter provides an overview and examples to date that have contributed to the rise of precision medicine and highlight areas where effort is needed to realize the full potential of these applications.

Full Text

Duke Authors

Cited Authors

  • Ginsburg, GS; Haga, SB

Published Date

  • January 1, 2018

Book Title

  • Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics: Foundations

Start / End Page

  • 21 - 45

International Standard Book Number 13 (ISBN-13)

  • 9780128126851

Digital Object Identifier (DOI)

  • 10.1016/B978-0-12-812537-3.00002-0

Citation Source

  • Scopus