Particulated juvenile articular cartilage allograft transplantation for osteochondral lesions of the knee and ankle.

Journal Article (Journal Article;Review)

Introduction: Osteochondral lesions have been challenging to treat due to the limited regenerative capacity of native hyaline cartilage. Although surgical options are available, a newer technique, Particulated Juvenile Cartilage Allograft Transplantation (PJCAT) has shown promise for lesions of the knee and ankle. Short-term studies have been encouraging of its use, but there is still limited evidence of its long-term durability.Areas covered: This review will summarize the surgical options currently available for osteochondral lesions, outline the indications and contraindications of PJCAT, present the basic science and clinical evidence of the procedure, and describe the surgical approaches of this technique.Expert opinion: PJCAT is a promising method to treat osteochondral lesions. However, continued research is needed to document the efficacy of this technique and potential superiority over other techniques. Benefits include ease of application, potential for arthroscopic or minimally invasive delivery, no need for perpendicular access, no donor site morbidity, and delivery of viable chondrocytes in hyaline cartilage.

Full Text

Duke Authors

Cited Authors

  • Wixted, CM; Dekker, TJ; Adams, SB

Published Date

  • March 2020

Published In

Volume / Issue

  • 17 / 3

Start / End Page

  • 235 - 244

PubMed ID

  • 32090633

Electronic International Standard Serial Number (EISSN)

  • 1745-2422

Digital Object Identifier (DOI)

  • 10.1080/17434440.2020.1733973


  • eng

Conference Location

  • England