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ElectroConvulsive therapy Cognitive Assessment (ECCA) tool: A new instrument to monitor cognitive function in patients undergoing ECT.

Publication ,  Journal Article
Hermida, AP; Goldstein, FC; Loring, DW; McClintock, SM; Weiner, RD; Reti, IM; Janjua, AU; Ye, Z; Peng, L; Tang, Y-L; Galendez, GC; Husain, MM ...
Published in: J Affect Disord
May 15, 2020

BACKGROUND: Electroconvulsive therapy (ECT) is a well-established treatment for severe depression but may result in adverse cognitive effects. Available cognitive screening instruments are nonspecific to the cognitive deficits associated with ECT. An ECT-cognitive assessment tool which can be easily administered was developed and validated in a clinical setting. METHODS: One hundred and thirty-six participants were enrolled. The ElectroConvulsive therapy Cognitive Assessment (ECCA) and the Montreal Cognitive Assessment (MoCA) were administered prospectively to 55 participants with major depressive disorder (MDD) undergoing ECT at three time points: pre-treatment, before the sixth treatment and one-week post-treatment. The psychometric properties of the total and domain scores were evaluated at all three time points. Forty demographically comparable participants with MDD who did not receive ECT, and 41 healthy, age-matched controls were evaluated at a single time point. RESULTS: ECCA and MoCA scores were not statistically different at baseline. Prior to the sixth and final ECT session, total ECCA scores were significantly lower than the MoCA total scores. The ECCA domains of subjective memory, informant-assessed memory, attention, autobiographical memory and delayed verbal recall were significantly lower post-ECT compared to pre-ECT. LIMITATIONS: The ECCA was compared only to the MoCA rather than to a more comprehensive neuropsychological testing. This limitation reflected the real-life clinical burden of performing full neuropsychological testing at three time points during the treatment course. CONCLUSIONS: The ECCA is a brief, reliable, bedside cognitive screening assessment tool that may be useful to monitor cognitive function in patients treated with ECT. The test can be downloaded from fuquacenter.org/ecca.

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Published In

J Affect Disord

DOI

EISSN

1573-2517

Publication Date

May 15, 2020

Volume

269

Start / End Page

36 / 42

Location

Netherlands

Related Subject Headings

  • Treatment Outcome
  • Psychiatry
  • Neuropsychological Tests
  • Humans
  • Electroconvulsive Therapy
  • Depressive Disorder, Major
  • Cognition Disorders
  • Cognition
  • 52 Psychology
  • 42 Health sciences
 

Citation

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Chicago
ICMJE
MLA
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Hermida, A. P., Goldstein, F. C., Loring, D. W., McClintock, S. M., Weiner, R. D., Reti, I. M., … National Network of Depression Centers ECT Task Group, . (2020). ElectroConvulsive therapy Cognitive Assessment (ECCA) tool: A new instrument to monitor cognitive function in patients undergoing ECT. J Affect Disord, 269, 36–42. https://doi.org/10.1016/j.jad.2020.03.010
Hermida, Adriana P., Felicia C. Goldstein, David W. Loring, Shawn M. McClintock, Richard D. Weiner, Irving M. Reti, A Umair Janjua, et al. “ElectroConvulsive therapy Cognitive Assessment (ECCA) tool: A new instrument to monitor cognitive function in patients undergoing ECT.J Affect Disord 269 (May 15, 2020): 36–42. https://doi.org/10.1016/j.jad.2020.03.010.
Hermida AP, Goldstein FC, Loring DW, McClintock SM, Weiner RD, Reti IM, et al. ElectroConvulsive therapy Cognitive Assessment (ECCA) tool: A new instrument to monitor cognitive function in patients undergoing ECT. J Affect Disord. 2020 May 15;269:36–42.
Hermida, Adriana P., et al. “ElectroConvulsive therapy Cognitive Assessment (ECCA) tool: A new instrument to monitor cognitive function in patients undergoing ECT.J Affect Disord, vol. 269, May 2020, pp. 36–42. Pubmed, doi:10.1016/j.jad.2020.03.010.
Hermida AP, Goldstein FC, Loring DW, McClintock SM, Weiner RD, Reti IM, Janjua AU, Ye Z, Peng L, Tang Y-L, Galendez GC, Husain MM, Maixner DF, Riva-Posse P, McDonald WM, National Network of Depression Centers ECT Task Group. ElectroConvulsive therapy Cognitive Assessment (ECCA) tool: A new instrument to monitor cognitive function in patients undergoing ECT. J Affect Disord. 2020 May 15;269:36–42.
Journal cover image

Published In

J Affect Disord

DOI

EISSN

1573-2517

Publication Date

May 15, 2020

Volume

269

Start / End Page

36 / 42

Location

Netherlands

Related Subject Headings

  • Treatment Outcome
  • Psychiatry
  • Neuropsychological Tests
  • Humans
  • Electroconvulsive Therapy
  • Depressive Disorder, Major
  • Cognition Disorders
  • Cognition
  • 52 Psychology
  • 42 Health sciences