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Prevalence and sociodemographic factors associated with depression among hospitalized patients with head and neck cancer-Results from a national study.

Publication ,  Journal Article
Rohde, RL; Adjei Boakye, E; Challapalli, SD; Patel, SH; Geneus, CJ; Tobo, BB; Simpson, MC; Mohammed, KA; Deshields, T; Varvares, MA; Osazuwa-Peters, N
Published in: Psychooncology
December 2018

OBJECTIVE: Depression is a significant problem for patients with head and neck cancer (HNC). This study explored the prevalence of and sociodemographic and clinical factors associated with depression, among patients with HNC. METHODS: We performed a retrospective analysis of 71 541 cases of HNC using a national dataset, the Nationwide Inpatient Sample, from 2008 to 2013. Weighted, multivariate logistic regression analysis estimated association between sociodemographic/clinical factors and tumor anatomical site with diagnosis of a major depressive disorder. RESULTS: Overall prevalence of major depressive disorder in HNC was 9.3%; highest prevalence was found in patients with laryngeal cancer (28.5%). Compared with laryngeal cancer, there were lower odds of depression among patients with oral cavity cancer (adjusted odds ratio [aOR] = 0.90; 95% CI, 0.84-0.97) and other anatomic sites (aOR = 0.87; 95% CI, 0.81-0.94), except oropharyngeal cancer (aOR = 1.00; 95% CI, 0.93-1.08). For every unit increase in comorbidities, odds of depression increased by 20% (aOR = 1.20; 95% CI, 1.19-1.23). Sociodemographic factors associated with increased odds of depression included being female (aOR = 1.77; 95% CI, 1.68-1.87), white (aOR = 1.75; 95% CI, 1.59-1.92), and having Medicaid (aOR = 1.09; 95% CI, 1.01-1.19) or Medicare insurance (aOR = 1.19; 95% CI, 1.10-1.27). CONCLUSIONS: Depression odds vary depending on HNC anatomic site, and one in four patients with laryngeal cancer may be depressed. Since depression is prevalent in this survivor cohort, it is important that psychosocial assessment and intervention are integrated into mainstream clinical care for patients with HNC.

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Published In

Psychooncology

DOI

EISSN

1099-1611

Publication Date

December 2018

Volume

27

Issue

12

Start / End Page

2809 / 2814

Location

England

Related Subject Headings

  • United States
  • Risk Factors
  • Retrospective Studies
  • Prevalence
  • Oncology & Carcinogenesis
  • Odds Ratio
  • Middle Aged
  • Male
  • Humans
  • Hospitalization
 

Citation

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Rohde, R. L., Adjei Boakye, E., Challapalli, S. D., Patel, S. H., Geneus, C. J., Tobo, B. B., … Osazuwa-Peters, N. (2018). Prevalence and sociodemographic factors associated with depression among hospitalized patients with head and neck cancer-Results from a national study. Psychooncology, 27(12), 2809–2814. https://doi.org/10.1002/pon.4893
Rohde, Rebecca L., Eric Adjei Boakye, Sai Deepika Challapalli, Shivam H. Patel, Christian J. Geneus, Betelihem B. Tobo, Matthew C. Simpson, et al. “Prevalence and sociodemographic factors associated with depression among hospitalized patients with head and neck cancer-Results from a national study.Psychooncology 27, no. 12 (December 2018): 2809–14. https://doi.org/10.1002/pon.4893.
Rohde RL, Adjei Boakye E, Challapalli SD, Patel SH, Geneus CJ, Tobo BB, et al. Prevalence and sociodemographic factors associated with depression among hospitalized patients with head and neck cancer-Results from a national study. Psychooncology. 2018 Dec;27(12):2809–14.
Rohde, Rebecca L., et al. “Prevalence and sociodemographic factors associated with depression among hospitalized patients with head and neck cancer-Results from a national study.Psychooncology, vol. 27, no. 12, Dec. 2018, pp. 2809–14. Pubmed, doi:10.1002/pon.4893.
Rohde RL, Adjei Boakye E, Challapalli SD, Patel SH, Geneus CJ, Tobo BB, Simpson MC, Mohammed KA, Deshields T, Varvares MA, Osazuwa-Peters N. Prevalence and sociodemographic factors associated with depression among hospitalized patients with head and neck cancer-Results from a national study. Psychooncology. 2018 Dec;27(12):2809–2814.
Journal cover image

Published In

Psychooncology

DOI

EISSN

1099-1611

Publication Date

December 2018

Volume

27

Issue

12

Start / End Page

2809 / 2814

Location

England

Related Subject Headings

  • United States
  • Risk Factors
  • Retrospective Studies
  • Prevalence
  • Oncology & Carcinogenesis
  • Odds Ratio
  • Middle Aged
  • Male
  • Humans
  • Hospitalization