Model systems for regeneration: Drosophila.

Journal Article (Journal Article;Review)

Drosophila melanogaster has historically been a workhorse model organism for studying developmental biology. In addition, Drosophila is an excellent model for studying how damaged tissues and organs can regenerate. Recently, new precision approaches that enable both highly targeted injury and genetic manipulation have accelerated progress in this field. Here, we highlight these techniques and review examples of recently discovered mechanisms that regulate regeneration in Drosophila larval and adult tissues. We also discuss how, by applying these powerful approaches, studies of Drosophila can continue to guide the future of regeneration research.

Full Text

Duke Authors

Cited Authors

  • Fox, DT; Cohen, E; Smith-Bolton, R

Published Date

  • April 6, 2020

Published In

Volume / Issue

  • 147 / 7

PubMed ID

  • 32253254

Pubmed Central ID

  • PMC7157589

Electronic International Standard Serial Number (EISSN)

  • 1477-9129

Digital Object Identifier (DOI)

  • 10.1242/dev.173781


  • eng

Conference Location

  • England