NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, Version 1.2020.

Journal Article (Journal Article)

The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic provide recommendations for genetic testing and counseling for hereditary cancer syndromes, and risk management recommendations for patients who are diagnosed with syndromes associated with an increased risk of these cancers. The NCCN panel meets at least annually to review comments, examine relevant new data, and reevaluate and update recommendations. These NCCN Guidelines Insights summarize the panel's discussion and most recent recommendations regarding criteria for high-penetrance genes associated with breast and ovarian cancer beyond BRCA1/2, pancreas screening and genes associated with pancreatic cancer, genetic testing for the purpose of systemic therapy decision-making, and testing for people with Ashkenazi Jewish ancestry.

Full Text

Duke Authors

Cited Authors

  • Daly, MB; Pilarski, R; Yurgelun, MB; Berry, MP; Buys, SS; Dickson, P; Domchek, SM; Elkhanany, A; Friedman, S; Garber, JE; Goggins, M; Hutton, ML; Khan, S; Klein, C; Kohlmann, W; Kurian, AW; Laronga, C; Litton, JK; Mak, JS; Menendez, CS; Merajver, SD; Norquist, BS; Offit, K; Pal, T; Pederson, HJ; Reiser, G; Shannon, KM; Visvanathan, K; Weitzel, JN; Wick, MJ; Wisinski, KB; Dwyer, MA; Darlow, SD

Published Date

  • April 2020

Published In

Volume / Issue

  • 18 / 4

Start / End Page

  • 380 - 391

PubMed ID

  • 32259785

Electronic International Standard Serial Number (EISSN)

  • 1540-1413

Digital Object Identifier (DOI)

  • 10.6004/jnccn.2020.0017

Language

  • eng

Conference Location

  • United States