Cancer Vaccines for Solid Tumors

Book Section

Since the late 19th century, when William Coley first injected cancer patients with "Coley's Toxin," we have been searching for a method of inoculation that will effectively harness the power of the immune system to destroy cancer cells. In the realm of solid tumors, multiple vaccines have been developed with this goal in mind. These vaccines conform to one of five strategies: dendritic cell vaccines, tumor cell vaccines, protein-based vaccines, viral vaccines, or an anti-idiotypic antibody vaccine. In this chapter, we comprehensively describe the successes of each of these strategies, focusing on vaccines that have made it to phase III trials.

Full Text

Duke Authors

Cited Authors

  • Vreeland, TJ; Herbert, GS; Peoples, GE

Published Date

  • April 13, 2018

Book Title

  • Immunotherapy in Translational Cancer Research

Start / End Page

  • 72 - 90

International Standard Book Number 13 (ISBN-13)

  • 9781118123225

Digital Object Identifier (DOI)

  • 10.1002/9781118684535.ch6

Citation Source

  • Scopus