ImPlementation REsearCh to DEvelop Interventions for People Living with HIV (the PRECluDE consortium): Combatting chronic disease comorbidities in HIV populations through implementation research.

Journal Article (Journal Article;Review)

Antiretroviral therapy (ART) prevented premature mortality and improved the quality of life among people living with the human immunodeficiency virus (PLWH), such that now more than half of PLWH in the United States are 50 years of age and older. Increased longevity among PLWH has resulted in a significant rise in chronic, comorbid diseases. However, the implementation of guideline-based interventions for preventing, treating, and managing such age-related, chronic conditions among the HIV population is lacking. The PRECluDE consortium supported by the Center for Translation Research and Implementation Science at the National Heart, Lung, and Blood Institute catalyzes implementation research on proven-effective interventions for co-occurring heart, lung, blood, and sleep diseases and conditions among PLWH. These collaborative research studies use novel implementation frameworks with HIV, mental health, cardiovascular, and pulmonary care to advance comprehensive HIV and chronic disease healthcare in a variety of settings and among diverse populations.

Full Text

Duke Authors

Cited Authors

  • Gamble-George, JC; Longenecker, CT; Webel, AR; Au, DH; Brown, AF; Bosworth, H; Crothers, K; Cunningham, WE; Fiscella, KA; Hamilton, AB; Helfrich, CD; Ladapo, JA; Luque, A; Tobin, JN; Wyatt, GE; Implementation Research to Develop Interventions for People Living with HIV (PRECluDE) Consortium,

Published Date

  • March 2020

Published In

Volume / Issue

  • 63 / 2

Start / End Page

  • 79 - 91

PubMed ID

  • 32199901

Pubmed Central ID

  • PMC7237329

Electronic International Standard Serial Number (EISSN)

  • 1873-1740

Digital Object Identifier (DOI)

  • 10.1016/j.pcad.2020.03.006


  • eng

Conference Location

  • United States