Adapting to a Pandemic - Conducting Oncology Trials during the SARS-CoV-2 Pandemic.

Journal Article (Journal Article)

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic has necessitated changes in cancer care delivery as resources are reallocated. Clinical trials and other research activities are inevitably impacted. Start-up activities for new trials may be deferred and recruitment suspended. For patients already enrolled however, there are challenges in continuing treatment on trial. Regulatory bodies have issued guidance on managing clinical trials during the pandemic, including contingency measures for remote study visits, delivery of investigational product, and site monitoring visits. New cancer clinical trial practices during the SARS-CoV-2 pandemic include new risk assessment strategies, decentralized and remote trial coordination, data collection, and delegation of specific therapeutic activities. This experience could provide evidence of more feasible and cost-effective methods for future clinical trial conduct.

Full Text

Duke Authors

Cited Authors

  • Tan, AC; Ashley, DM; Khasraw, M

Published Date

  • July 1, 2020

Published In

Volume / Issue

  • 26 / 13

Start / End Page

  • 3100 - 3103

PubMed ID

  • 32312892

Pubmed Central ID

  • PMC7357670

Electronic International Standard Serial Number (EISSN)

  • 1557-3265

Digital Object Identifier (DOI)

  • 10.1158/1078-0432.CCR-20-1364

Language

  • eng

Conference Location

  • United States