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Genetic basis for divergence in developmental gene expression in two closely related sea urchins.

Publication ,  Journal Article
Wang, L; Israel, JW; Edgar, A; Raff, RA; Raff, EC; Byrne, M; Wray, GA
Published in: Nature ecology & evolution
June 2020

The genetic basis for divergence in developmental gene expression among species is poorly understood, despite growing evidence that such changes underlie many interesting traits. Here we quantify transcription in hybrids of Heliocidaris tuberculata and Heliocidaris erythrogramma, two closely related sea urchins with highly divergent developmental gene expression and life histories. We find that most expression differences between species result from genetic influences that affect one stage of development, indicating limited pleiotropic consequences for most mutations that contribute to divergence in gene expression. Activation of zygotic transcription is broadly delayed in H. erythrogramma, the species with the derived life history, despite its overall faster premetamorphic development. Altered expression of several terminal differentiation genes associated with the derived larval morphology of H. erythrogramma is based largely on differences in the expression or function of their upstream regulators, providing insights into the genetic basis for the evolution of key life history traits.

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Published In

Nature ecology & evolution

DOI

EISSN

2397-334X

ISSN

2397-334X

Publication Date

June 2020

Volume

4

Issue

6

Start / End Page

831 / 840

Related Subject Headings

  • Sea Urchins
  • Phenotype
  • Larva
  • Genes, Developmental
  • Gene Expression
  • Animals
  • 4104 Environmental management
  • 3104 Evolutionary biology
  • 3103 Ecology
 

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Wang, L., Israel, J. W., Edgar, A., Raff, R. A., Raff, E. C., Byrne, M., & Wray, G. A. (2020). Genetic basis for divergence in developmental gene expression in two closely related sea urchins. Nature Ecology & Evolution, 4(6), 831–840. https://doi.org/10.1038/s41559-020-1165-y
Wang, Lingyu, Jennifer W. Israel, Allison Edgar, Rudolf A. Raff, Elizabeth C. Raff, Maria Byrne, and Gregory A. Wray. “Genetic basis for divergence in developmental gene expression in two closely related sea urchins.Nature Ecology & Evolution 4, no. 6 (June 2020): 831–40. https://doi.org/10.1038/s41559-020-1165-y.
Wang L, Israel JW, Edgar A, Raff RA, Raff EC, Byrne M, et al. Genetic basis for divergence in developmental gene expression in two closely related sea urchins. Nature ecology & evolution. 2020 Jun;4(6):831–40.
Wang, Lingyu, et al. “Genetic basis for divergence in developmental gene expression in two closely related sea urchins.Nature Ecology & Evolution, vol. 4, no. 6, June 2020, pp. 831–40. Epmc, doi:10.1038/s41559-020-1165-y.
Wang L, Israel JW, Edgar A, Raff RA, Raff EC, Byrne M, Wray GA. Genetic basis for divergence in developmental gene expression in two closely related sea urchins. Nature ecology & evolution. 2020 Jun;4(6):831–840.

Published In

Nature ecology & evolution

DOI

EISSN

2397-334X

ISSN

2397-334X

Publication Date

June 2020

Volume

4

Issue

6

Start / End Page

831 / 840

Related Subject Headings

  • Sea Urchins
  • Phenotype
  • Larva
  • Genes, Developmental
  • Gene Expression
  • Animals
  • 4104 Environmental management
  • 3104 Evolutionary biology
  • 3103 Ecology