Transmission Potential of Asymptomatic and Paucisymptomatic Severe Acute Respiratory Syndrome Coronavirus 2 Infections: A 3-Family Cluster Study in China.


Journal Article

Data concerning the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in asymptomatic and paucisymptomatic patients are lacking. We report a 3-family cluster of infections involving asymptomatic and paucisymptomatic transmission. Eight of 15 (53%) members from 3 families were confirmed with SARS-CoV-2 infection. Of 8 patients, 3 were asymptomatic and 1 was paucisymptomatic. An asymptomatic mother transmitted the virus to her son, and a paucisymptomatic father transmitted the virus to his 3-month-old daughter. SARS-CoV-2 was detected in the environment of 1 household. The complete genomes of SARS-CoV-2 from the patients were > 99.9% identical and were clustered with other SARS-CoV-2 sequences reported from China and other countries.

Full Text

Duke Authors

Cited Authors

  • Jiang, X-L; Zhang, X-L; Zhao, X-N; Li, C-B; Lei, J; Kou, Z-Q; Sun, W-K; Hang, Y; Gao, F; Ji, S-X; Lin, C-F; Pang, B; Yao, M-X; Anderson, BD; Wang, G-L; Yao, L; Duan, L-J; Kang, D-M; Ma, M-J

Published Date

  • June 2020

Published In

Volume / Issue

  • 221 / 12

Start / End Page

  • 1948 - 1952

PubMed ID

  • 32319519

Pubmed Central ID

  • 32319519

Electronic International Standard Serial Number (EISSN)

  • 1537-6613

International Standard Serial Number (ISSN)

  • 0022-1899

Digital Object Identifier (DOI)

  • 10.1093/infdis/jiaa206


  • eng