The phosphorylated isoform of microtubule associated protein 1B (MAP1B) is expressed in the visual system of the tench (Tinca tinca, L) during optic nerve regeneration.

Journal Article (Journal Article)

By using Western blot analysis and immunohistochemistry we have demonstrated that microtubule associated protein 1B (MAP1B)-phos is present in growing and regenerating axons of retinal ganglion cells of fish (Tinca tinca, L). We have found that the levels of MAP1B-phos substantially increase in regenerating optic nerves. Our observations suggest that MAP1 B-phos plays an important role in regeneration processes in the central nervous system (CNS) of the fish. These results are compared in the present paper with that found in the regenerating peripheral nervous system (PNS) of mammals.

Full Text

Duke Authors

Cited Authors

  • Vecino, E; Ulloa, L; Avila, J

Published Date

  • April 3, 1998

Published In

Volume / Issue

  • 245 / 2

Start / End Page

  • 93 - 96

PubMed ID

  • 9605493

International Standard Serial Number (ISSN)

  • 0304-3940

Digital Object Identifier (DOI)

  • 10.1016/s0304-3940(98)00188-8


  • eng

Conference Location

  • Ireland