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Impact of exercise on the immune system and outcomes in hematologic malignancies.

Publication ,  Journal Article
Sitlinger, A; Brander, DM; Bartlett, DB
Published in: Blood Adv
April 28, 2020

Exercise is increasingly recognized as important to cancer care. The biology of how exercise improves outcomes is not well understood, however. Studies show that exercise favorably influences the immune system in healthy individuals (neutrophils, monocytes, natural killer cells, T cells, and a number of cytokines). Thus, exercise in patients with hematologic cancer could significantly improve immune function and tumor microenvironment. We performed a literature search and identified 7 studies examining exercise and the immune environment in hematologic malignancies. This review focuses on the role of exercise and physical activity on the immune system in hematologic malignancies and healthy adults.

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Published In

Blood Adv

DOI

EISSN

2473-9537

Publication Date

April 28, 2020

Volume

4

Issue

8

Start / End Page

1801 / 1811

Location

United States

Related Subject Headings

  • Tumor Microenvironment
  • Killer Cells, Natural
  • Humans
  • Hematologic Neoplasms
  • Exercise
  • Adult
  • 3201 Cardiovascular medicine and haematology
 

Citation

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Sitlinger, A., Brander, D. M., & Bartlett, D. B. (2020). Impact of exercise on the immune system and outcomes in hematologic malignancies. Blood Adv, 4(8), 1801–1811. https://doi.org/10.1182/bloodadvances.2019001317
Sitlinger, Andrea, Danielle M. Brander, and David B. Bartlett. “Impact of exercise on the immune system and outcomes in hematologic malignancies.Blood Adv 4, no. 8 (April 28, 2020): 1801–11. https://doi.org/10.1182/bloodadvances.2019001317.
Sitlinger A, Brander DM, Bartlett DB. Impact of exercise on the immune system and outcomes in hematologic malignancies. Blood Adv. 2020 Apr 28;4(8):1801–11.
Sitlinger, Andrea, et al. “Impact of exercise on the immune system and outcomes in hematologic malignancies.Blood Adv, vol. 4, no. 8, Apr. 2020, pp. 1801–11. Pubmed, doi:10.1182/bloodadvances.2019001317.
Sitlinger A, Brander DM, Bartlett DB. Impact of exercise on the immune system and outcomes in hematologic malignancies. Blood Adv. 2020 Apr 28;4(8):1801–1811.

Published In

Blood Adv

DOI

EISSN

2473-9537

Publication Date

April 28, 2020

Volume

4

Issue

8

Start / End Page

1801 / 1811

Location

United States

Related Subject Headings

  • Tumor Microenvironment
  • Killer Cells, Natural
  • Humans
  • Hematologic Neoplasms
  • Exercise
  • Adult
  • 3201 Cardiovascular medicine and haematology