Pediatric Acute Lymphoblastic Leukemia, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology.

Journal Article (Journal Article)

Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy. Advancements in technology that enhance our understanding of the biology of the disease, risk-adapted therapy, and enhanced supportive care have contributed to improved survival rates. However, additional clinical management is needed to improve outcomes for patients classified as high risk at presentation (eg, T-ALL, infant ALL) and who experience relapse. The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for pediatric ALL provide recommendations on the workup, diagnostic evaluation, and treatment of the disease, including guidance on supportive care, hematopoietic stem cell transplantation, and pharmacogenomics. This portion of the NCCN Guidelines focuses on the frontline and relapsed/refractory management of pediatric ALL.

Full Text

Duke Authors

Cited Authors

  • Brown, P; Inaba, H; Annesley, C; Beck, J; Colace, S; Dallas, M; DeSantes, K; Kelly, K; Kitko, C; Lacayo, N; Larrier, N; Maese, L; Mahadeo, K; Nanda, R; Nardi, V; Rodriguez, V; Rossoff, J; Schuettpelz, L; Silverman, L; Sun, J; Sun, W; Teachey, D; Wong, V; Yanik, G; Johnson-Chilla, A; Ogba, N

Published Date

  • January 2020

Published In

Volume / Issue

  • 18 / 1

Start / End Page

  • 81 - 112

PubMed ID

  • 31910389

Electronic International Standard Serial Number (EISSN)

  • 1540-1413

Digital Object Identifier (DOI)

  • 10.6004/jnccn.2020.0001


  • eng

Conference Location

  • United States