The Project Baseline Health Study: a step towards a broader mission to map human health.

Journal Article (Journal Article;Review)

The Project Baseline Health Study (PBHS) was launched to map human health through a comprehensive understanding of both the health of an individual and how it relates to the broader population. The study will contribute to the creation of a biomedical information system that accounts for the highly complex interplay of biological, behavioral, environmental, and social systems. The PBHS is a prospective, multicenter, longitudinal cohort study that aims to enroll thousands of participants with diverse backgrounds who are representative of the entire health spectrum. Enrolled participants will be evaluated serially using clinical, molecular, imaging, sensor, self-reported, behavioral, psychological, environmental, and other health-related measurements. An initial deeply phenotyped cohort will inform the development of a large, expanded virtual cohort. The PBHS will contribute to precision health and medicine by integrating state of the art testing, longitudinal monitoring and participant engagement, and by contributing to the development of an improved platform for data sharing and analysis.

Full Text

Duke Authors

Cited Authors

  • Arges, K; Assimes, T; Bajaj, V; Balu, S; Bashir, MR; Beskow, L; Blanco, R; Califf, R; Campbell, P; Carin, L; Christian, V; Cousins, S; Das, M; Dockery, M; Douglas, PS; Dunham, A; Eckstrand, J; Fleischmann, D; Ford, E; Fraulo, E; French, J; Gambhir, SS; Ginsburg, GS; Green, RC; Haddad, F; Hernandez, A; Hernandez, J; Huang, ES; Jaffe, G; King, D; Koweek, LH; Langlotz, C; Liao, YJ; Mahaffey, KW; Marcom, K; Marks, WJ; Maron, D; McCabe, R; McCall, S; McCue, R; Mega, J; Miller, D; Muhlbaier, LH; Munshi, R; Newby, LK; Pak-Harvey, E; Patrick-Lake, B; Pencina, M; Peterson, ED; Rodriguez, F; Shore, S; Shah, S; Shipes, S; Sledge, G; Spielman, S; Spitler, R; Schaack, T; Swamy, G; Willemink, MJ; Wong, CA

Published Date

  • 2020

Published In

Volume / Issue

  • 3 /

Start / End Page

  • 84 -

PubMed ID

  • 32550652

Pubmed Central ID

  • PMC7275087

Electronic International Standard Serial Number (EISSN)

  • 2398-6352

Digital Object Identifier (DOI)

  • 10.1038/s41746-020-0290-y


  • eng

Conference Location

  • England