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Treatment of Locally Advanced Esophageal Carcinoma: ASCO Guideline.

Publication ,  Journal Article
Shah, MA; Kennedy, EB; Catenacci, DV; Deighton, DC; Goodman, KA; Malhotra, NK; Willett, C; Stiles, B; Sharma, P; Tang, L; Wijnhoven, BPL ...
Published in: J Clin Oncol
August 10, 2020

PURPOSE: To develop an evidence-based clinical practice guideline to assist in clinical decision making for patients with locally advanced esophageal cancer. METHODS: ASCO convened an Expert Panel to conduct a systematic review of the more recently published literature (1999-2019) on therapy options for patients with locally advanced esophageal cancer and provide recommended care options for this patient population. RESULTS: Seventeen randomized controlled trials met the inclusion criteria. Where possible, data were extracted separately for squamous cell carcinoma and adenocarcinoma. RECOMMENDATIONS: Multimodality therapy for patients with locally advanced esophageal carcinoma is recommended. For the subgroup of patients with adenocarcinoma, preoperative chemoradiotherapy or perioperative chemotherapy should be offered. For the subgroup of patients with squamous cell carcinoma, preoperative chemoradiotherapy or chemoradiotherapy without surgery should be offered. Additional subgroup considerations are provided to assist with implementation of these recommendations. Additional information is available at www.asco.org/gastrointestinal-cancer-guidelines.

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Published In

J Clin Oncol

DOI

EISSN

1527-7755

Publication Date

August 10, 2020

Volume

38

Issue

23

Start / End Page

2677 / 2694

Location

United States

Related Subject Headings

  • Randomized Controlled Trials as Topic
  • Oncology & Carcinogenesis
  • Humans
  • Esophageal Neoplasms
  • Combined Modality Therapy
  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis
  • 1103 Clinical Sciences
 

Citation

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Shah, M. A., Kennedy, E. B., Catenacci, D. V., Deighton, D. C., Goodman, K. A., Malhotra, N. K., … Hofstetter, W. L. (2020). Treatment of Locally Advanced Esophageal Carcinoma: ASCO Guideline. J Clin Oncol, 38(23), 2677–2694. https://doi.org/10.1200/JCO.20.00866
Shah, Manish A., Erin B. Kennedy, Daniel V. Catenacci, Dana C. Deighton, Karyn A. Goodman, Narinder K. Malhotra, Christopher Willett, et al. “Treatment of Locally Advanced Esophageal Carcinoma: ASCO Guideline.J Clin Oncol 38, no. 23 (August 10, 2020): 2677–94. https://doi.org/10.1200/JCO.20.00866.
Shah MA, Kennedy EB, Catenacci DV, Deighton DC, Goodman KA, Malhotra NK, et al. Treatment of Locally Advanced Esophageal Carcinoma: ASCO Guideline. J Clin Oncol. 2020 Aug 10;38(23):2677–94.
Shah, Manish A., et al. “Treatment of Locally Advanced Esophageal Carcinoma: ASCO Guideline.J Clin Oncol, vol. 38, no. 23, Aug. 2020, pp. 2677–94. Pubmed, doi:10.1200/JCO.20.00866.
Shah MA, Kennedy EB, Catenacci DV, Deighton DC, Goodman KA, Malhotra NK, Willett C, Stiles B, Sharma P, Tang L, Wijnhoven BPL, Hofstetter WL. Treatment of Locally Advanced Esophageal Carcinoma: ASCO Guideline. J Clin Oncol. 2020 Aug 10;38(23):2677–2694.

Published In

J Clin Oncol

DOI

EISSN

1527-7755

Publication Date

August 10, 2020

Volume

38

Issue

23

Start / End Page

2677 / 2694

Location

United States

Related Subject Headings

  • Randomized Controlled Trials as Topic
  • Oncology & Carcinogenesis
  • Humans
  • Esophageal Neoplasms
  • Combined Modality Therapy
  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis
  • 1103 Clinical Sciences