Acoustofluidic Holography for Micro- to Nanoscale Particle Manipulation.

Journal Article (Journal Article)

Acoustic-based techniques can manipulate particles in a label-free, contact-free, and biocompatible manner. However, most previous work in acoustic manipulation has been constrained by axisymmetric patterns of pressure nodes and antinodes. Acoustic holography is an emerging technique that offers the potential to generate arbitrary pressure distributions which can be applied to particle manipulation with higher degrees of freedom. However, since current acoustic holography techniques rely on acoustic radiation forces, which decrease dramatically when the target particle size decreases, they have difficulty manipulating particles in the micro/nanoscale. Here, we introduce a holography technique that leverages both an arbitrary acoustic field and controllable fluid motion to offer an effective approach for manipulating micro/nano particles. Our approach, termed acoustofluidic holography (AFH), can manipulate a variety of materials, including cells, polymers, and metals, across sizes ranging from hundreds of micrometers to tens of nanometers.

Full Text

Duke Authors

Cited Authors

  • Gu, Y; Chen, C; Rufo, J; Shen, C; Wang, Z; Huang, P-H; Fu, H; Zhang, P; Cummer, SA; Tian, Z; Huang, TJ

Published Date

  • November 2020

Published In

Volume / Issue

  • 14 / 11

Start / End Page

  • 14635 - 14645

PubMed ID

  • 32574491

Pubmed Central ID

  • PMC7688555

Electronic International Standard Serial Number (EISSN)

  • 1936-086X

International Standard Serial Number (ISSN)

  • 1936-0851

Digital Object Identifier (DOI)

  • 10.1021/acsnano.0c03754


  • eng