Broadening primate genomics: new insights into the ecology and evolution of primate gene regulation.

Journal Article (Review;Journal Article)

Comparative analyses have played a key role in understanding how gene regulatory evolution contributes to primate phenotypic diversity. Recently, these studies have expanded to include a wider range of species, within-population as well as interspecific analyses, and research on wild as well as captive individuals. This expansion provides context for understanding genetic and environmental effects on gene regulation in humans, including the importance of the pathogen and social environments. Although taxonomic representation remains biased, inclusion of more species has also begun to reveal the evolutionary processes that explain whether and when gene regulation is conserved. Together, this work highlights how studies in other primates contribute to understanding evolution in our own lineage, and we conclude by identifying promising avenues for future work.

Full Text

Duke Authors

Cited Authors

  • Anderson, JA; Vilgalys, TP; Tung, J

Published Date

  • June 20, 2020

Published In

Volume / Issue

  • 62 /

Start / End Page

  • 16 - 22

PubMed ID

  • 32569794

Pubmed Central ID

  • PMC7483836

Electronic International Standard Serial Number (EISSN)

  • 1879-0380

International Standard Serial Number (ISSN)

  • 0959-437X

Digital Object Identifier (DOI)

  • 10.1016/j.gde.2020.05.009


  • eng