MimickNet, Mimicking Clinical Image Post- Processing Under Black-Box Constraints.

Journal Article (Journal Article)

Image post-processing is used in clinical-grade ultrasound scanners to improve image quality (e.g., reduce speckle noise and enhance contrast). These post-processing techniques vary across manufacturers and are generally kept proprietary, which presents a challenge for researchers looking to match current clinical-grade workflows. We introduce a deep learning framework, MimickNet, that transforms conventional delay-and-summed (DAS) beams into the approximate Dynamic Tissue Contrast Enhanced (DTCE™) post-processed images found on Siemens clinical-grade scanners. Training MimickNet only requires post-processed image samples from a scanner of interest without the need for explicit pairing to DAS data. This flexibility allows MimickNet to hypothetically approximate any manufacturer's post-processing without access to the pre-processed data. MimickNet post-processing achieves a 0.940 ± 0.018 structural similarity index measurement (SSIM) compared to clinical-grade post-processing on a 400 cine-loop test set, 0.937 ± 0.025 SSIM on a prospectively acquired dataset, and 0.928 ± 0.003 SSIM on an out-of-distribution cardiac cine-loop after gain adjustment. To our knowledge, this is the first work to establish deep learning models that closely approximate ultrasound post-processing found in current medical practice. MimickNet serves as a clinical post-processing baseline for future works in ultrasound image formation to compare against. Additionally, it can be used as a pretrained model for fine-tuning towards different post-processing techniques. To this end, we have made the MimickNet software, phantom data, and permitted in vivo data open-source at https://github.com/ouwen/MimickNet.

Full Text

Duke Authors

Cited Authors

  • Huang, O; Long, W; Bottenus, N; Lerendegui, M; Trahey, GE; Farsiu, S; Palmeri, ML

Published Date

  • June 2020

Published In

Volume / Issue

  • 39 / 6

Start / End Page

  • 2277 - 2286

PubMed ID

  • 32012003

Pubmed Central ID

  • PMC7286793

Electronic International Standard Serial Number (EISSN)

  • 1558-254X

International Standard Serial Number (ISSN)

  • 0278-0062

Digital Object Identifier (DOI)

  • 10.1109/tmi.2020.2970867


  • eng