Recent advances in genome editing and creation of genetically modified pigs.

Journal Article (Review;Journal Article)

The field of xenotransplantation is benefiting greatly from recent advances in genetic engineering. The efficiency and pace with which new model animals are being created has dramatically sped progress towards clinical relevance. Endonuclease-driven genome editing now allows for the efficient generation of targeted genetic alterations. Herein we review the available methods of genetic engineering that have been successfully employed to create genetically modified pigs.

Full Text

Duke Authors

Cited Authors

  • Butler, JR; Ladowski, JM; Martens, GR; Tector, M; Tector, AJ

Published Date

  • November 2015

Published In

Volume / Issue

  • 23 / Pt B

Start / End Page

  • 217 - 222

PubMed ID

  • 26231992

Electronic International Standard Serial Number (EISSN)

  • 1743-9159

International Standard Serial Number (ISSN)

  • 1743-9191

Digital Object Identifier (DOI)

  • 10.1016/j.ijsu.2015.07.684


  • eng