Skip to main content
Journal cover image

The effect of sarcopenia on perioperative complications in abdominally based free-flap breast reconstruction.

Publication ,  Journal Article
Broyles, JM; Smith, JM; Phillips, BT; Mericli, AF; Selber, JC; Largo, RD; Baumann, DP; Liu, J; Schaverien, MV
Published in: J Surg Oncol
November 2020

PURPOSE: The identification of patient-specific risk factors, which predict morbidity following abdominally based microvascular breast reconstruction is difficult. Sarcopenia is a proxy for patient frailty and is an independent predictor of complications in a myriad of surgical disciplines. We predict that sarcopenic patients will be at higher risk for surgical complications following abdominally based microvascular breast reconstruction. METHODS: A retrospective study of all patients who underwent delayed abdominally based autologous breast reconstruction following postmastectomy radiation therapy from 2007 to 2013 at a single institution was conducted. Univariate and multiple logistic regression models were used to assess the effect of sarcopenia on postoperative outcomes. RESULTS: Two hundred and eight patients met the inclusion criteria, of which 30 met criteria for sarcopenia (14.1%). There were no significant differences in demographics between groups. There were no significant differences in minor (36.7% vs 44.4%; P = .43) or major (16.7% vs 25.3%; P = .36) complications between groups as well as hospital length of stay. Multivariable logistic regression demonstrated that a staged reconstruction with the use of a tissue expander was the only consistent variable, which predicted major complications (OR, 2.24; 95% CI, 1.18-4.64; P = .015). CONCLUSIONS: Sarcopenia does not predispose to minor or major surgical complications in patients who undergo abdominally based microsurgical breast reconstruction.

Duke Scholars

Published In

J Surg Oncol

DOI

EISSN

1096-9098

Publication Date

November 2020

Volume

122

Issue

6

Start / End Page

1240 / 1246

Location

United States

Related Subject Headings

  • Transplantation, Autologous
  • Sarcopenia
  • Retrospective Studies
  • Prospective Studies
  • Prognosis
  • Postoperative Complications
  • Perioperative Care
  • Oncology & Carcinogenesis
  • Middle Aged
  • Mastectomy
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Broyles, J. M., Smith, J. M., Phillips, B. T., Mericli, A. F., Selber, J. C., Largo, R. D., … Schaverien, M. V. (2020). The effect of sarcopenia on perioperative complications in abdominally based free-flap breast reconstruction. J Surg Oncol, 122(6), 1240–1246. https://doi.org/10.1002/jso.26120
Broyles, Justin M., Jeffrey M. Smith, Brett T. Phillips, Alex F. Mericli, Jesse C. Selber, Rene D. Largo, Donald P. Baumann, Jessie Liu, and Mark V. Schaverien. “The effect of sarcopenia on perioperative complications in abdominally based free-flap breast reconstruction.J Surg Oncol 122, no. 6 (November 2020): 1240–46. https://doi.org/10.1002/jso.26120.
Broyles JM, Smith JM, Phillips BT, Mericli AF, Selber JC, Largo RD, et al. The effect of sarcopenia on perioperative complications in abdominally based free-flap breast reconstruction. J Surg Oncol. 2020 Nov;122(6):1240–6.
Broyles, Justin M., et al. “The effect of sarcopenia on perioperative complications in abdominally based free-flap breast reconstruction.J Surg Oncol, vol. 122, no. 6, Nov. 2020, pp. 1240–46. Pubmed, doi:10.1002/jso.26120.
Broyles JM, Smith JM, Phillips BT, Mericli AF, Selber JC, Largo RD, Baumann DP, Liu J, Schaverien MV. The effect of sarcopenia on perioperative complications in abdominally based free-flap breast reconstruction. J Surg Oncol. 2020 Nov;122(6):1240–1246.
Journal cover image

Published In

J Surg Oncol

DOI

EISSN

1096-9098

Publication Date

November 2020

Volume

122

Issue

6

Start / End Page

1240 / 1246

Location

United States

Related Subject Headings

  • Transplantation, Autologous
  • Sarcopenia
  • Retrospective Studies
  • Prospective Studies
  • Prognosis
  • Postoperative Complications
  • Perioperative Care
  • Oncology & Carcinogenesis
  • Middle Aged
  • Mastectomy