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Racial Disparity in Response to Prostate Cancer Systemic Therapies.

Publication ,  Journal Article
Bitting, RL; Goodman, M; George, DJ
Published in: Curr Oncol Rep
July 23, 2020

PURPOSE OF REVIEW: In this review, we aim to describe racial differences in response to treatment for metastatic castration-resistant prostate cancer (mCRPC). RECENT FINDINGS: Recent data suggests that, despite higher risk features, African Americans may respond better than Caucasians to systemic therapies for advanced prostate cancer. This improved response is not limited to one class of drugs but can be seen with androgen-pathway directed therapies, chemotherapy, bone-targeted therapy, and immunotherapy. The mechanisms for this are being further explored. African Americans may respond better to mCRPC treatments but validation in prospective clinical trials is needed.

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Published In

Curr Oncol Rep

DOI

EISSN

1534-6269

Publication Date

July 23, 2020

Volume

22

Issue

9

Start / End Page

96

Location

United States

Related Subject Headings

  • White People
  • Prostatic Neoplasms
  • Oncology & Carcinogenesis
  • Male
  • Immunotherapy
  • Humans
  • Healthcare Disparities
  • Black or African American
  • Androgen Antagonists
  • 3211 Oncology and carcinogenesis
 

Citation

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Bitting, R. L., Goodman, M., & George, D. J. (2020). Racial Disparity in Response to Prostate Cancer Systemic Therapies. Curr Oncol Rep, 22(9), 96. https://doi.org/10.1007/s11912-020-00966-z
Bitting, Rhonda L., Michael Goodman, and Daniel J. George. “Racial Disparity in Response to Prostate Cancer Systemic Therapies.Curr Oncol Rep 22, no. 9 (July 23, 2020): 96. https://doi.org/10.1007/s11912-020-00966-z.
Bitting RL, Goodman M, George DJ. Racial Disparity in Response to Prostate Cancer Systemic Therapies. Curr Oncol Rep. 2020 Jul 23;22(9):96.
Bitting, Rhonda L., et al. “Racial Disparity in Response to Prostate Cancer Systemic Therapies.Curr Oncol Rep, vol. 22, no. 9, July 2020, p. 96. Pubmed, doi:10.1007/s11912-020-00966-z.
Bitting RL, Goodman M, George DJ. Racial Disparity in Response to Prostate Cancer Systemic Therapies. Curr Oncol Rep. 2020 Jul 23;22(9):96.
Journal cover image

Published In

Curr Oncol Rep

DOI

EISSN

1534-6269

Publication Date

July 23, 2020

Volume

22

Issue

9

Start / End Page

96

Location

United States

Related Subject Headings

  • White People
  • Prostatic Neoplasms
  • Oncology & Carcinogenesis
  • Male
  • Immunotherapy
  • Humans
  • Healthcare Disparities
  • Black or African American
  • Androgen Antagonists
  • 3211 Oncology and carcinogenesis