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Five-year outcomes of endovascular repair of complicated acute type B aortic dissections.

Publication ,  Journal Article
Bavaria, JE; Brinkman, WT; Hughes, GC; Shah, AS; Charlton-Ouw, KM; Azizzadeh, A; White, RA
Published in: J Thorac Cardiovasc Surg
February 2022

OBJECTIVE: Thoracic endovascular aortic repair is the standard of care for acute complicated type B aortic dissections, but long-term single-device outcomes are limited. METHODS: Fifty patients were treated with the Valiant Captivia thoracic stent graft (Medtronic Inc, Santa Rosa, Calif) for acute complicated type B aortic dissections in this prospective, nonrandomized Dissection Trial. All-cause mortality, secondary procedures, and serious adverse events were assessed, and a core lab evaluated images for aortic remodeling. RESULTS: Compliance for both clinical and imaging follow-up was 78% (18 out of 23) for the available patients at 5 years. Notable baseline characteristics were 86% of patients (43 out of 50) had malperfusion, 20% (10 out of 50) had ruptures, and 94% (46 out of 49) had DeBakey class IIIB dissections. The 5-year freedom from dissection-related mortality, secondary procedures related to the dissection, and endoleaks was 83%, 86%, and 85%, respectively. After 5 years, 89% of patients (16 out of 18) had a completely thrombosed false lumen in the stented segment of the aorta and the true lumen diameter over the length of stent graft was stable or increased for 94% of patients (16 out of 17) while the false lumen diameter was stable or decreased in 77% (13 out of 17) after 5 years. CONCLUSIONS: In the Dissection Trial, patients experienced positive and sustained measures of aortic remodeling. Survival outcomes, need for secondary procedures, and adverse event rates were consistent with previous thoracic endovascular aortic repair studies. Although limitations exist with the follow-up compliance, the Valiant Captivia thoracic stent graft system was effective in the long-term management of acute complicated type B aortic dissections in this patient population with a challenging condition.

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Published In

J Thorac Cardiovasc Surg

DOI

EISSN

1097-685X

Publication Date

February 2022

Volume

163

Issue

2

Start / End Page

539 / 548.e2

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Time Factors
  • Stents
  • Respiratory System
  • Reoperation
  • Prospective Studies
  • Postoperative Complications
  • Middle Aged
  • Male
  • Humans
 

Citation

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Bavaria, J. E., Brinkman, W. T., Hughes, G. C., Shah, A. S., Charlton-Ouw, K. M., Azizzadeh, A., & White, R. A. (2022). Five-year outcomes of endovascular repair of complicated acute type B aortic dissections. J Thorac Cardiovasc Surg, 163(2), 539-548.e2. https://doi.org/10.1016/j.jtcvs.2020.03.162
Bavaria, Joseph E., William T. Brinkman, G Chad Hughes, Aamir S. Shah, Kristofer M. Charlton-Ouw, Ali Azizzadeh, and Rodney A. White. “Five-year outcomes of endovascular repair of complicated acute type B aortic dissections.J Thorac Cardiovasc Surg 163, no. 2 (February 2022): 539-548.e2. https://doi.org/10.1016/j.jtcvs.2020.03.162.
Bavaria JE, Brinkman WT, Hughes GC, Shah AS, Charlton-Ouw KM, Azizzadeh A, et al. Five-year outcomes of endovascular repair of complicated acute type B aortic dissections. J Thorac Cardiovasc Surg. 2022 Feb;163(2):539-548.e2.
Bavaria, Joseph E., et al. “Five-year outcomes of endovascular repair of complicated acute type B aortic dissections.J Thorac Cardiovasc Surg, vol. 163, no. 2, Feb. 2022, pp. 539-548.e2. Pubmed, doi:10.1016/j.jtcvs.2020.03.162.
Bavaria JE, Brinkman WT, Hughes GC, Shah AS, Charlton-Ouw KM, Azizzadeh A, White RA. Five-year outcomes of endovascular repair of complicated acute type B aortic dissections. J Thorac Cardiovasc Surg. 2022 Feb;163(2):539-548.e2.
Journal cover image

Published In

J Thorac Cardiovasc Surg

DOI

EISSN

1097-685X

Publication Date

February 2022

Volume

163

Issue

2

Start / End Page

539 / 548.e2

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Time Factors
  • Stents
  • Respiratory System
  • Reoperation
  • Prospective Studies
  • Postoperative Complications
  • Middle Aged
  • Male
  • Humans