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After 62 years of regulating immunity, dexamethasone meets COVID-19.

Publication ,  Journal Article
Cain, DW; Cidlowski, JA
Published in: Nat Rev Immunol
October 2020

Six months into the COVID-19 pandemic, effective treatments have been frustratingly sparse. The RECOVERY clinical trial, however, revealed that treatment with dexamethasone, a classic synthetic glucocorticoid, enhanced survival of critically ill patients with COVID-19. In this Comment, we discuss the immunological impacts of glucocorticoid therapy for COVID-19.

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Published In

Nat Rev Immunol

DOI

EISSN

1474-1741

Publication Date

October 2020

Volume

20

Issue

10

Start / End Page

587 / 588

Location

England

Related Subject Headings

  • Time Factors
  • Severity of Illness Index
  • SARS-CoV-2
  • Receptors, Glucocorticoid
  • Randomized Controlled Trials as Topic
  • Pneumonia, Viral
  • Pandemics
  • Immunosuppressive Agents
  • Immunology
  • Immunity, Innate
 

Citation

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Cain, D. W., & Cidlowski, J. A. (2020). After 62 years of regulating immunity, dexamethasone meets COVID-19. Nat Rev Immunol, 20(10), 587–588. https://doi.org/10.1038/s41577-020-00421-x
Cain, Derek W., and John A. Cidlowski. “After 62 years of regulating immunity, dexamethasone meets COVID-19.Nat Rev Immunol 20, no. 10 (October 2020): 587–88. https://doi.org/10.1038/s41577-020-00421-x.
Cain DW, Cidlowski JA. After 62 years of regulating immunity, dexamethasone meets COVID-19. Nat Rev Immunol. 2020 Oct;20(10):587–8.
Cain, Derek W., and John A. Cidlowski. “After 62 years of regulating immunity, dexamethasone meets COVID-19.Nat Rev Immunol, vol. 20, no. 10, Oct. 2020, pp. 587–88. Pubmed, doi:10.1038/s41577-020-00421-x.
Cain DW, Cidlowski JA. After 62 years of regulating immunity, dexamethasone meets COVID-19. Nat Rev Immunol. 2020 Oct;20(10):587–588.

Published In

Nat Rev Immunol

DOI

EISSN

1474-1741

Publication Date

October 2020

Volume

20

Issue

10

Start / End Page

587 / 588

Location

England

Related Subject Headings

  • Time Factors
  • Severity of Illness Index
  • SARS-CoV-2
  • Receptors, Glucocorticoid
  • Randomized Controlled Trials as Topic
  • Pneumonia, Viral
  • Pandemics
  • Immunosuppressive Agents
  • Immunology
  • Immunity, Innate