RSSs set the odds for exclusion.
Publication
, Journal Article
Krangel, MS
Published in: J Exp Med
September 7, 2020
In this issue of JEM, Wu et al. (https://doi.org/10.1084/jem.20200412) provide new insights into allelic exclusion. They demonstrate that Vβ-to-DβJβ rearrangement occurs stochastically on two competing Tcrb alleles, with suboptimal Vβ recombination signal sequences limiting synchronous rearrangements and essential for allelic exclusion.
Duke Scholars
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Published In
J Exp Med
DOI
EISSN
1540-9538
Publication Date
September 7, 2020
Volume
217
Issue
9
Location
United States
Related Subject Headings
- Recombination, Genetic
- Receptors, Antigen, T-Cell, alpha-beta
- Protein Sorting Signals
- Immunology
- Alleles
- 42 Health sciences
- 32 Biomedical and clinical sciences
- 11 Medical and Health Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Krangel, M. S. (2020). RSSs set the odds for exclusion. J Exp Med, 217(9). https://doi.org/10.1084/jem.20200831
Krangel, Michael S. “RSSs set the odds for exclusion.” J Exp Med 217, no. 9 (September 7, 2020). https://doi.org/10.1084/jem.20200831.
Krangel MS. RSSs set the odds for exclusion. J Exp Med. 2020 Sep 7;217(9).
Krangel, Michael S. “RSSs set the odds for exclusion.” J Exp Med, vol. 217, no. 9, Sept. 2020. Pubmed, doi:10.1084/jem.20200831.
Krangel MS. RSSs set the odds for exclusion. J Exp Med. 2020 Sep 7;217(9).
Published In
J Exp Med
DOI
EISSN
1540-9538
Publication Date
September 7, 2020
Volume
217
Issue
9
Location
United States
Related Subject Headings
- Recombination, Genetic
- Receptors, Antigen, T-Cell, alpha-beta
- Protein Sorting Signals
- Immunology
- Alleles
- 42 Health sciences
- 32 Biomedical and clinical sciences
- 11 Medical and Health Sciences