PURPOSE: To assess the feasibility of an on-site, case-based curriculum delivered by preceptors and to assess preceptors' perceptions of the impact of the curriculum on rotation performance and ability to teach. METHODS: Hospital medicine preceptors were surveyed before and after curriculum deployment using a previously developed survey. RESULTS: Preceptors had positive perceptions of the impact of the curriculum. Rotation performance for health care systems topics had the greatest increase. CONCLUSIONS: Curriculum delivery through on-site, case-based teaching might be well received by preceptors. Despite increased demands on preceptor time, preceptor response to the introduction of a structured curriculum during the second-year internal medicine rotation was positive. Use of preceptor-delivered, preprepared, case-based curricular content might be a tool worth testing in further contexts.