Mechanisms of NOD-like receptor-associated inflammasome activation.
Journal Article (Journal Article;Review)
A major function of a subfamily of NLR (nucleotide-binding domain, leucine-rich repeat containing, or NOD-like receptor) proteins is in inflammasome activation, which has been implicated in a multitude of disease models and human diseases. This work will highlight key progress in understanding the mechanisms that activate the best-studied NLRs (NLRP3, NLRC4, NAIP, and NLRP1) and in uncovering inflammasome NLRs.
- Wen, H; Miao, EA; Ting, JP-Y
- September 19, 2013
Volume / Issue
- 39 / 3
Start / End Page
- 432 - 441
Pubmed Central ID
Electronic International Standard Serial Number (EISSN)
Digital Object Identifier (DOI)
- United States