Mechanisms of NOD-like receptor-associated inflammasome activation.
Publication
, Journal Article
Wen, H; Miao, EA; Ting, JP-Y
Published in: Immunity
September 19, 2013
A major function of a subfamily of NLR (nucleotide-binding domain, leucine-rich repeat containing, or NOD-like receptor) proteins is in inflammasome activation, which has been implicated in a multitude of disease models and human diseases. This work will highlight key progress in understanding the mechanisms that activate the best-studied NLRs (NLRP3, NLRC4, NAIP, and NLRP1) and in uncovering inflammasome NLRs.
Duke Scholars
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Published In
Immunity
DOI
EISSN
1097-4180
Publication Date
September 19, 2013
Volume
39
Issue
3
Start / End Page
432 / 441
Location
United States
Related Subject Headings
- Signal Transduction
- Receptors, Cytoplasmic and Nuclear
- Neuronal Apoptosis-Inhibitory Protein
- NLR Proteins
- NLR Family, Pyrin Domain-Containing 3 Protein
- Mice
- Inflammasomes
- Immunology
- Humans
- Enzyme Activation
Citation
APA
Chicago
ICMJE
MLA
NLM
Wen, H., Miao, E. A., & Ting, J.-Y. (2013). Mechanisms of NOD-like receptor-associated inflammasome activation. Immunity, 39(3), 432–441. https://doi.org/10.1016/j.immuni.2013.08.037
Wen, Haitao, Edward A. Miao, and Jenny P-Y Ting. “Mechanisms of NOD-like receptor-associated inflammasome activation.” Immunity 39, no. 3 (September 19, 2013): 432–41. https://doi.org/10.1016/j.immuni.2013.08.037.
Wen H, Miao EA, Ting JP-Y. Mechanisms of NOD-like receptor-associated inflammasome activation. Immunity. 2013 Sep 19;39(3):432–41.
Wen, Haitao, et al. “Mechanisms of NOD-like receptor-associated inflammasome activation.” Immunity, vol. 39, no. 3, Sept. 2013, pp. 432–41. Pubmed, doi:10.1016/j.immuni.2013.08.037.
Wen H, Miao EA, Ting JP-Y. Mechanisms of NOD-like receptor-associated inflammasome activation. Immunity. 2013 Sep 19;39(3):432–441.
Published In
Immunity
DOI
EISSN
1097-4180
Publication Date
September 19, 2013
Volume
39
Issue
3
Start / End Page
432 / 441
Location
United States
Related Subject Headings
- Signal Transduction
- Receptors, Cytoplasmic and Nuclear
- Neuronal Apoptosis-Inhibitory Protein
- NLR Proteins
- NLR Family, Pyrin Domain-Containing 3 Protein
- Mice
- Inflammasomes
- Immunology
- Humans
- Enzyme Activation