Abdominal Wall Transplantation

Journal Article (Journal Article)

Abdominal wall vascularized composite allotransplantation (AW-VCA) is a relatively young field within transplantation with 21 reported cases to date in the last decade. All AW-VCAs have been performed on patients undergoing either simultaneous multivisceral transplantation (MVT) or intestinal transplantation (IT). The two approaches to AW-VCA described are macrovascular and microvascular approaches. While at the time that this review is written, only three institutions have performed this procedure; their outcomes have shown low allograft loss. In addition, acute rejection of the abdominal wall graft was uncommon and successfully treated with standard measures. A comparison of each institution’s operative technique, maintenance immunosuppression regimen, and rejection management provide insight regarding the feasibility of AW-VCAs. AW-VCA has proven to serve as a viable option for patients undergoing multivisceral or intestinal transplantation with a donor and recipient size mismatch. Further experience with AW-VCA will aid in better defining its indications and help standardize technique and management.

Full Text

Duke Authors

Cited Authors

  • Avashia, YJ; Mackert, GA; May, B; Erdmann, D; Ravindra, KV

Published Date

  • September 1, 2015

Published In

Volume / Issue

  • 2 / 3

Start / End Page

  • 269 - 275

Electronic International Standard Serial Number (EISSN)

  • 2196-3029

Digital Object Identifier (DOI)

  • 10.1007/s40472-015-0070-9

Citation Source

  • Scopus