"Inactive" ingredients in oral medications.

Journal Article (Review;Journal Article)

Oral forms of medications contain "inactive" ingredients to enhance their physical properties. Using data analytics, we characterized the abundance and complexity of inactive ingredients in approved medications. A majority of medications contain ingredients that could cause adverse reactions, underscoring the need to maximize the tolerability and safety of medications and their inactive ingredients.

Full Text

Duke Authors

Cited Authors

  • Reker, D; Blum, SM; Steiger, C; Anger, KE; Sommer, JM; Fanikos, J; Traverso, G

Published Date

  • March 2019

Published In

Volume / Issue

  • 11 / 483

PubMed ID

  • 30867323

Pubmed Central ID

  • PMC7122736

Electronic International Standard Serial Number (EISSN)

  • 1946-6242

International Standard Serial Number (ISSN)

  • 1946-6234

Digital Object Identifier (DOI)

  • 10.1126/scitranslmed.aau6753

Language

  • eng