This Duke-Margolis report out provides a framework for public health officials and community leaders in schools, businesses and other institutions on how to use Covid-19 screening test strategies to operate safely and prevent further spread of the virus. A National Decision Point: Effective Testing and Screening for Covid-19, was developed with funding from the Rockefeller Foundation, and aims to be a useful tool to help officials customize screening strategies of asymptomatic people to local circumstances and risk – with a particular focus on higher-risk populations and suppressing community spread.