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An open resource for transdiagnostic research in pediatric mental health and learning disorders.

Publication ,  Journal Article
Alexander, LM; Escalera, J; Ai, L; Andreotti, C; Febre, K; Mangone, A; Vega-Potler, N; Langer, N; Alexander, A; Kovacs, M; Litke, S; Bui, A ...
Published in: Scientific data
December 2017

Technological and methodological innovations are equipping researchers with unprecedented capabilities for detecting and characterizing pathologic processes in the developing human brain. As a result, ambitions to achieve clinically useful tools to assist in the diagnosis and management of mental health and learning disorders are gaining momentum. To this end, it is critical to accrue large-scale multimodal datasets that capture a broad range of commonly encountered clinical psychopathology. The Child Mind Institute has launched the Healthy Brain Network (HBN), an ongoing initiative focused on creating and sharing a biobank of data from 10,000 New York area participants (ages 5-21). The HBN Biobank houses data about psychiatric, behavioral, cognitive, and lifestyle phenotypes, as well as multimodal brain imaging (resting and naturalistic viewing fMRI, diffusion MRI, morphometric MRI), electroencephalography, eye-tracking, voice and video recordings, genetics and actigraphy. Here, we present the rationale, design and implementation of HBN protocols. We describe the first data release (n=664) and the potential of the biobank to advance related areas (e.g., biophysical modeling, voice analysis).

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Published In

Scientific data

DOI

EISSN

2052-4463

ISSN

2052-4463

Publication Date

December 2017

Volume

4

Start / End Page

170181

Related Subject Headings

  • Young Adult
  • Neuroimaging
  • Multimodal Imaging
  • Mental Health
  • Learning Disabilities
  • Humans
  • Electroencephalography
  • Databases, Factual
  • Child
  • Adolescent
 

Citation

APA
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ICMJE
MLA
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Alexander, L. M., Escalera, J., Ai, L., Andreotti, C., Febre, K., Mangone, A., … Milham, M. P. (2017). An open resource for transdiagnostic research in pediatric mental health and learning disorders. Scientific Data, 4, 170181. https://doi.org/10.1038/sdata.2017.181
Alexander, Lindsay M., Jasmine Escalera, Lei Ai, Charissa Andreotti, Karina Febre, Alexander Mangone, Natan Vega-Potler, et al. “An open resource for transdiagnostic research in pediatric mental health and learning disorders.Scientific Data 4 (December 2017): 170181. https://doi.org/10.1038/sdata.2017.181.
Alexander LM, Escalera J, Ai L, Andreotti C, Febre K, Mangone A, et al. An open resource for transdiagnostic research in pediatric mental health and learning disorders. Scientific data. 2017 Dec;4:170181.
Alexander, Lindsay M., et al. “An open resource for transdiagnostic research in pediatric mental health and learning disorders.Scientific Data, vol. 4, Dec. 2017, p. 170181. Epmc, doi:10.1038/sdata.2017.181.
Alexander LM, Escalera J, Ai L, Andreotti C, Febre K, Mangone A, Vega-Potler N, Langer N, Alexander A, Kovacs M, Litke S, O’Hagan B, Andersen J, Bronstein B, Bui A, Bushey M, Butler H, Castagna V, Camacho N, Chan E, Citera D, Clucas J, Cohen S, Dufek S, Eaves M, Fradera B, Gardner J, Grant-Villegas N, Green G, Gregory C, Hart E, Harris S, Horton M, Kahn D, Kabotyanski K, Karmel B, Kelly SP, Kleinman K, Koo B, Kramer E, Lennon E, Lord C, Mantello G, Margolis A, Merikangas KR, Milham J, Minniti G, Neuhaus R, Levine A, Osman Y, Parra LC, Pugh KR, Racanello A, Restrepo A, Saltzman T, Septimus B, Tobe R, Waltz R, Williams A, Yeo A, Castellanos FX, Klein A, Paus T, Leventhal BL, Craddock RC, Koplewicz HS, Milham MP. An open resource for transdiagnostic research in pediatric mental health and learning disorders. Scientific data. 2017 Dec;4:170181.

Published In

Scientific data

DOI

EISSN

2052-4463

ISSN

2052-4463

Publication Date

December 2017

Volume

4

Start / End Page

170181

Related Subject Headings

  • Young Adult
  • Neuroimaging
  • Multimodal Imaging
  • Mental Health
  • Learning Disabilities
  • Humans
  • Electroencephalography
  • Databases, Factual
  • Child
  • Adolescent