Obesity-related asthma in children: A role for vitamin D.
Journal Article (Review;Journal Article)
Excess adipose tissue predisposes to an enhanced inflammatory state and can contribute to the pathogenesis and severity of asthma. Vitamin D has anti-inflammatory properties and low-serum levels are seen in children with asthma and in children with obesity. Here we review the intersection of asthma, obesity, and hypovitaminosis D in children. Supplementation with vitamin D has been proposed as a simple, safe, and inexpensive adjunctive therapy in a number of disease states. However, little research has examined the pharmacokinetics of vitamin D and its therapeutic potential in children who suffer from obesity-related asthma.
Full Text
Duke Authors
Cited Authors
- O'Sullivan, BP; James, L; Majure, JM; Bickel, S; Phan, L-T; Serrano Gonzalez, M; Staples, H; Tam-Williams, J; Lang, J; Snowden, J; IDeA States Pediatric Clinical Trials Network,
Published Date
- February 2021
Published In
Volume / Issue
- 56 / 2
Start / End Page
- 354 - 361
PubMed ID
- 32930511
Pubmed Central ID
- PMC8341445
Electronic International Standard Serial Number (EISSN)
- 1099-0496
International Standard Serial Number (ISSN)
- 8755-6863
Digital Object Identifier (DOI)
- 10.1002/ppul.25053
Language
- eng