Development of an Item Bank to Measure Medication Adherence: Systematic Review.

Journal Article (Systematic Review;Journal Article)

Background

Medication adherence is important in managing the progression of chronic diseases. A promising approach to reduce cognitive burden when measuring medication adherence lies in the use of computer-adaptive tests (CATs) or in the development of shorter patient-reported outcome measures (PROMs). However, the lack of an item bank currently hampers this progress.

Objective

We aim to develop an item bank to measure general medication adherence.

Methods

Using the preferred reporting items for systematic review and meta-analysis (PRISMA), articles published before October 2019 were retrieved from PubMed, Embase, CINAHL, the Cochrane Library, and Web of Science. Items from existing PROMs were classified and selected ("binned" and "winnowed") according to standards published by the Patient-Reported Outcomes Measurement Information System (PROMIS) Cooperative Group.

Results

A total of 126 unique PROMs were identified from 213 studies in 48 countries. Items from the literature review (47 PROMs with 579 items for which permission has been obtained) underwent binning and winnowing. This resulted in 421 candidate items (77 extent of adherence and 344 reasons for adherence).

Conclusions

We developed an item bank for measuring general medication adherence using items from validated PROMs. This will allow researchers to create new PROMs from selected items and provide the foundation to develop CATs.

Full Text

Duke Authors

Cited Authors

  • Kwan, YH; Oo, LJY; Loh, DHF; Phang, JK; Weng, SD; Blalock, DV; Chew, EH; Yap, KZ; Tan, CYK; Yoon, S; Fong, W; Østbye, T; Low, LL; Bosworth, HB; Thumboo, J

Published Date

  • October 8, 2020

Published In

Volume / Issue

  • 22 / 10

Start / End Page

  • e19089 -

PubMed ID

  • 33030441

Pubmed Central ID

  • PMC7582150

Electronic International Standard Serial Number (EISSN)

  • 1438-8871

International Standard Serial Number (ISSN)

  • 1439-4456

Digital Object Identifier (DOI)

  • 10.2196/19089

Language

  • eng