Prescribing Patterns of Antihypertensive Medications in Low- and Middle-Income Countries: A Systematic Review.

Journal Article (Journal Article;Systematic Review)

Hypertension is highly prevalent, but its pharmacological management has not been well evaluated in low- and middle-income countries (LMICs). This review examined the prescribing patterns of antihypertensives in LMICs. Data were extracted from a total of 26 studies spanning the time period 2000 to 2018. In 10 studies, calcium channel blockers (CCBs) were the most frequently prescribed medication for managing hypertension (range = 33% to 72%); in six studies, renin angiotensin system (RAS) blockers (range = 25% to 83%); in five studies, diuretics (range = 39% to 99%); and in five studies, β-blockers (BBs; range = 26% to 49%) were the most commonly prescribed antihypertensive medications. Prescribing sedatives and sublingual administration of captopril for controlling hypertension was also reported in 3 studies. Only 10 studies presented their findings in light of national or international guidelines. This review calls for further antihypertensive utilization and dispensation studies and a better understanding of clinician's perception and practice of hypertension management guidelines in LMICs.

Full Text

Duke Authors

Cited Authors

  • Arshad, V; Samad, Z; Das, J; Almas, A; Rashid, N; Virani, SS; Bloomfield, GS; Jafar, TH; Ahmed, B

Published Date

  • January 2021

Published In

Volume / Issue

  • 33 / 1

Start / End Page

  • 14 - 22

PubMed ID

  • 33084371

Electronic International Standard Serial Number (EISSN)

  • 1941-2479

Digital Object Identifier (DOI)

  • 10.1177/1010539520965280


  • eng

Conference Location

  • China