BioSamplr: An open source, low cost automated sampling system for bioreactors


Journal Article

Abstract Autosampling from bioreactors reduces error, increases reproducibility and offers improved aseptic handling when compared to manual sampling. Additionally, autosampling greatly decreases the hands-on time required for a bioreactor experiment and enables sampling 24 hrs a day. We have designed, built and tested a low cost, open source, automated bioreactor sampling system, the BioSamplr. The BioSamplr can take up to ten samples from a bioreactor at a desired sample interval and cools them to a desired temperature. The device, assembled from low cost and 3D printed components, is controlled wirelessly by a Raspberry Pi, and records all sampling data to a log file. The cost and accessibility of the BioSamplr make it useful for laboratories without access to more expensive and complex autosampling systems.

Full Text

Duke Authors

Cited Authors

  • Efromson, J; Li, S; Lynch, M

Published Date

  • October 25, 2020

Pubmed Central ID

  • PPR:PPR230127

Digital Object Identifier (DOI)

  • 10.1101/2020.10.25.354183