Differences in Presentation and Outcomes in Males and Females With Branch Retinal Vein Occlusion.

Journal Article (Journal Article)

BACKGROUND AND OBJECTIVE: To investigate the effect of patient sex on presentation and outcomes of branch retinal vein occlusion (BRVO). PATIENTS AND METHODS: Retrospective chart review cohort study of 188 eyes with BRVO and cystoid macular edema (CME); 81 treatment-naïve eyes were selected for subgroup analysis. RESULTS: Males had better visual acuity (VA) in the BRVO eye at baseline compared to females (log-MAR: 0.49 ± 0.47 vs. 0.62 ± 0.53; P = .04); this was not present at the final visit (males: 0.41 ± 0.40 vs. females: 0.59 ± 0.60; P = .10). In treatment-naïve eyes, both sexes had similar VA at baseline (males: 0.42 ± 0.29 vs. females: 0.59 ± 0.46; P = .09); however, at the final visit, males had better VA compared to females (0.38 ± 0.43 vs. 0.66 ± 0.67; P = .03). On average, males received more anti-VEGF injections when adjusting for follow-up (P = .04). CONCLUSIONS: Significant sex differences in VA and treatment of eyes with BRVO and CME were noted. Further investigation is needed to understand sex differences in eyes with BRVO and CME. [Ophthalmic Surg Lasers Imaging Retina. 2020;51:564-572.].

Full Text

Duke Authors

Cited Authors

  • Mirzania, D; Thomas, AS; Stinnett, S; Fekrat, S

Published Date

  • October 1, 2020

Published In

Volume / Issue

  • 51 / 10

Start / End Page

  • 564 - 572

PubMed ID

  • 33104223

Electronic International Standard Serial Number (EISSN)

  • 2325-8179

Digital Object Identifier (DOI)

  • 10.3928/23258160-20201005-04

Language

  • eng

Conference Location

  • United States